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Enhanced anti-obesity effects of complex of resistant starch and chitosan in high fat diet fed rats

Planta 207, 604611 (1999)

In this context, the increased extracellular glutamate can bind to its receptor, the metabotropic glutamate receptor 5 (mGluR5) on the stellate cell surface, stimulating it to synthesize 2-arachidonoylglycerol (2-AG) [155], which in turn, once released into the extracellular space, binds to the cannabinoid receptor-1 (CB1R) on hepatocytes, triggering a mechanism of de novo lipogenesis and therefore of fat accumulation [156] (Figure 7)

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This alignment underscores why oxytosis/ferroptosis is implicated as a critical executioner of dopaminergic neurons

Because reduced glutathione oxidizes readily once in solution, reconstituted material should be kept at 28C and used promptly to preserve the reduced (GSH) form